Submission Tilte
Lymphomas in People Living with HIV (PLWH)
Submission Abstract:
In the era of combined antiretroviral therapy (cART), the incidence of lymphoma among people living with HIV (PLWH) surpassed Kaposi's sarcoma in 2011, becoming the most common AIDS-defining malignancy. The annual incidence rate ranges approximately from 100 to 300 per 100,000 individuals with HIV infection as the population denominator, which is 50 to 100 times higher than in non-HIV-infected populations. Lymphoma-related mortality has also become a leading cause of death among PLWH, posing significant global health concerns. However, the clinical features, prognostic markers, and pathogenesis of lymphoma in PLWH remain incompletely understood. Through this special issue, we aim to focus on the latest advancements in the understanding of HIV-related lymphoma, including its pathogenesis, clinical characteristics, prognostic factors, and exploration of treatment modalities.