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Current Neuropharmacology

Journal Impact Factor: 5.3

Scopus Cite Score: 10.0

Indexed in: Scopus, SCI Expanded, MEDLINE/PubMed

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Aims and Scope:

Aims and Scope: Current Neuropharmacology aims to provide current, comprehensive/mini reviews and guest edited issues of all areas of neuropharmacology and related matters of neuroscience. The reviews cover the fields of molecular, cellular, and systems/behavioural aspects of neuropharmacology and neuroscience. The journal serves as a comprehensive, multidisciplinary expert forum for neuropharmacologists and neuroscientists.

Editor-in-Chief:

Ferdinando Nicoletti Department of Pharmaceutical Sciences
University Rome"da Sapienza"
Rome
Italy

ISSN: 1570-159X (Print)

eISSN: 1875-6190 (Online)

Special Issues With Active Call for Papers

Submission closes on: Nov 06, 2026

Current Trends in Application of Large Language Models in Intelligent Medicine and Healthcare particularly neurodegenerative disorders

In this era of modern technology, there has been advanced progress in integrating artificial intelligence in chemoinformatics to accelerate the discovery of neurotherapeutics from natural and synthetic sources. This special issue could explore how AI-driven chemoinformatic tools are revolutionising the identification, profiling, and optimisation of bioactive compounds for the treatment of neurological diseases such as Alzheimer’s, Parkinson’s, epilepsy, and multiple sclerosis. Contributions could include machine learning models for predicting neuroactivity, virtual screening of natural product... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Mohammad Amjad Kamal
Co-Guest Editor(s): Prof. Bairong Shen,Nigel H. Greig

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Submission closes on: Oct 24, 2026

Plant-derived extracellular vesicles in brain aging and neurodegenerative diseases

Plant-derived extracellular vesicles (PDEVs) have recently emerged as both promising natural compounds and nanocarriers in the field of brain aging and neurodegenerative diseases. Owing to their biocompatibility, low immunogenicity, and intrinsic bioactive cargo, PDEVs offer an alternative drug delivery system. Increasing evidence suggests that PDEVs can easily cross biological barriers, including the blood-brain barrier, modulate oxidative stress, inflammation, and cellular senescence, addressing key pathological mechanisms underlying brain aging and neurodegenerative diseases. Beyond their therapeutic applications,... see more

Impact Factor: 5.3
Guest Editor(s): Metehan Uzun
Co-Guest Editor(s): Damla Aykora,Yıldızhan Şengül

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Submission closes on: Oct 03, 2026

New Approaches in Brain Injury and Neurodegenerative Disease: Converging Mechanisms and Therapeutic Frontiers

Brain injury and neurodegenerative diseases represent a continuum of neurological dysfunction marked by progressive cellular damage, impaired neuroplasticity, and cognitive decline. Although traditionally considered distinct, mounting evidence reveals shared pathophysiological mechanisms—including oxidative stress, mitochondrial dysfunction, excitotoxicity, and chronic neuroinflammation—that contribute to both acute and chronic neural deterioration. This special issue explores both the underlying mechanisms driving brain injury and neurodegeneration, and the innovative therapeutic strategies aimed at halting or reversing their progression. Topics include emerging... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Francisco Capani
Co-Guest Editor(s): Juan Pablo Luaces

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Submission closes on: Aug 21, 2026

Emerging Concepts in Mechanisms and Therapeutic Strategies for CNS Demyelinating Diseases

We are pleased to invite submissions for this special issue titled "Emerging Concepts in Mechanisms and Therapeutic Strategies for CNS Demyelinating Diseases." This issue aims to highlight recent advances in the understanding and management of central nervous system (CNS) demyelinating disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Although several FDA-approved disease-modifying therapies have significantly reduced relapse rates and radiologic activity in MS, therapeutic strategies targeting... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Smathorn Thakolwiboon
Co-Guest Editor(s): Dr. Pei Shang,Dr. Nisa Vorasoot

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Submission closes on: Aug 13, 2026

Neuropharmacology of Psychedelics

Classical psychedelics are driving a renewed effort to connect receptor-level pharmacology with circuit dynamics and therapeutic models. Foundational research and human pharmacology establish 5-HT2A signaling as central to their acute effects and candidate mechanisms of action. Recent randomized trials report clinically meaningful symptom reductions with psilocybin in treatment-resistant depression and with MDMA-assisted therapy in moderate-to-severe PTSD, motivating careful attention to efficacy, safety, and reproducibility. Converging preclinical and human studies indicate that these agents promote structural... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Mehmet Bostancıklıoglu

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Submission closes on: Jul 25, 2026

Advances in Neurovascular Unit in Stroke and Neurodegenerative Disease: Mechanisms and Therapeutic Frontiers

The main goal of this special issue is to analyze current knowledge of the functional roles of various types of cells in neurovascular units(NVU) in neurodegenerative diseases such as stroke, Alzheimer's disease, and Parkinson's disease. This issue invites research on the cellular and molecular mechanisms driving inflammation, blood-brain barrier(BBB) injury, oxidative stress response, autophagy, apoptosis, and necrosis in NVU. In addition, the topic seeks to emphasize therapeutic strategies aimed at regulating these mechanisms to protect... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Changxiang Li
Co-Guest Editor(s): Dr. Qingguo Wang,Dr. Xueqian Wang,Dr. Xiaoyu Xu,Dr. Yang Liu

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Submission closes on: Jul 03, 2026

Advances and Integrative Approaches to Gut-Brain Interactions

Disorders of gut-brain interaction (DGBIs), formerly known as functional gastrointestinal disorders, involve dysfunction of complex signaling pathways between the gastrointestinal tract and the central nervous system. These disorders span the esophagus (functional heartburn, functional dysphagia), stomach (functional dyspepsia), and intestines (irritable bowel syndrome, chronic constipation), and are increasingly recognized as multisystem syndromes influenced by neural, immune, endocrine, and microbial factors. Emerging neuropharmacological evidence highlights novel pharmacological therapies, neuromodulation, behavioral interventions, and integrative medicine approaches as... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Tao Bai
Co-Guest Editor(s): Dr. Gengqing Song,Dr. Runze Quan

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Submission closes on: Jun 14, 2026

Chinese Multidisciplinary Expert Consensus on the Neurotherapeutics: from Neurodegenerative Diseases to Cerebral Vascular Disease

Besides the excellent fields of science, humanities, aerospace, military, technology, industry, Clinical Neuroscience, as well as Neurology in China, have also made huge progress in the world. Therefore, the Special Issue Editor, would assume that it is deserved to organize Chinese Multidisciplinary Expert Consensus’ series on Neurology, especially in Neuropharmacology advances and clinical experience, following the paper of Chinese Multidisciplinary Expert Consensus on Orphan/Anticopper Drugs and Other Non-drug Management of Hepatolenticular Degeneration ( Wang XP…)... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Xiao Ping Wang

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Submission closes on: Jun 04, 2026

Innovative Neuroprotective Therapies for Acute Neurological Disorders

This special issue entitled “Innovative Neuroprotective Therapies for Acute Neurological Diseases” is dedicated to the latest strategies to mitigate brain injury and promote recovery in acute neurological diseases. Focusing on ischemic stroke, traumatic brain injury, spinal cord injury, cardiac arrest, status epilepticus and neonatal hypoxic-ischemic encephalopathy, this issue highlights the latest advances in neuroprotection. It looks at the mechanisms of action of neuroprotective agents, including pharmacological interventions, stem cell therapy and extracellular vesicles, which offer... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Denis Silachev
Co-Guest Editor(s): Dr. Artem Gureev

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Submission closes on: May 15, 2026

Advances in Neuroimaging: Bridging Pharmacology, Nanotechnology, and Neurological Disorders

This special topic seeks to compile cutting-edge research and reviews that explore the synergy between neuroimaging, pharmacology, and nanotechnology in understanding and treating neurological disorders. We aim to elucidate novel imaging biomarkers for tracking drug efficacy and disease progression in conditions such as Alzheimer’s, Parkinson’s, multiple sclerosis, and brain tumors. Highlight nanomaterial innovations (e.g., quantum dots, dendrimers, lipid nanoparticles) for improved imaging resolution, targeted or minimally invasive theranostics. Address neurotrauma applications, including imaging-guided interventions for... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Jianhua Liu
Co-Guest Editor(s): Dr. Yinghui Wang,Dr. Yang Liu

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Submission closes on: Apr 30, 2026

Cannabinoids in Health and Disease.

The role of cannabinoids in human physiology and disease has become a dynamic and rapidly evolving field of research, offering new insights into the potential of these compounds. With advancements in neuropharmacology and clinical trials, cannabinoids are now at the forefront of innovative approaches to treat several conditions. This special issue aims to bring together cutting-edge research and comprehensive reviews that explore the multifaceted role of cannabinoids in different pathophysiological contexts. The focus will be... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Rui Rodrigues
Co-Guest Editor(s): Dr. Ana Covelo,Dr. Livio Luongo

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Submission closes on: Feb 20, 2026

Cannabis for Health: Molecular Mechanism, Therapeutic Potentials, Clinical Application and Regulatory Challenges

Cannabis-based products span a history of over 4,000 years, with their regular purposes in numerous religious rituals, traditional systems of medicine, cosmetics, and hedonic activities. The discovery and cloning of cannabinoid receptors in mammalian tissues provided direct evidence of the physiological significance of targeting these receptors with endogenously synthesized and released ligands. The presence of the endocannabinoid system (ECS) in various parts of the nervous system and peripheral tissues has been associated with several physiological... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Md. Noushad Javed

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Submission closes on: Feb 07, 2026

Integrative Approaches to Neuropsychiatric Disorders: Pharmacology, Neuromodulation, and Beyond

Neuropsychiatric disorders are multifaceted neurological conditions that remain only partially understood. These disorders impact the brain's structure, the intricate networks of synaptic connections, and the delicate balance of neurotransmission. They are marked by disruptions in the cerebral cortex and limbic system, a reduction in neurogenesis, shifts in neural plasticity, and an upregulation of genes that predispose individuals to these conditions. The history of research and treatment for severe neuropsychiatric disorders is one of many claimed... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Zongshi Qin
Co-Guest Editor(s): Dr. Di Wang,Dr. Dong-Dong Shi,Dr. Yu Wang

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Submission closes on: Feb 05, 2026

Role of Small Molecular Substances in Neurological Diseases

This special topic will investigate a diverse array of applications of small molecular substances in the treatment of neurological diseases. This includes, but is not limited to, examining the roles and mechanisms of histamine, neuropeptide Y, and substance P in these conditions. The onset and progression of neurological diseases are associated with significant alterations in ion channel gene expression, synaptic transmission, synaptic plasticity, and neural circuitry. This special topic will examine the roles and mechanisms... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Qianxing Zhuang
Co-Guest Editor(s): Dr. Bin Li

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Submission closes on: Jan 18, 2026

Enhancing Neuropharmacology with Home Cage Monitoring, Advanced Delivery and Stimulation Technologies, and Artificial Intelligence

Home cage monitoring (HCM) technologies have revolutionized neuropharmacological research by enabling continuous, non-invasive observation of rodents in their natural environments. Complementary advancements such as 24/7 continuous drug delivery systems (e.g., implantable pumps) and wireless neurostimulation methods—including optogenetics—offer precise methods for modulating neural activity and administering pharmacological agents without disrupting the animals’ home cage environment. Integrating artificial intelligence (AI) into these systems enhances data analysis by uncovering subtle behavioral patterns and neural correlates that traditional approaches... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Stefano Gaburro
Co-Guest Editor(s): Dr. Anupam Sah

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Submission closes on: Jan 04, 2026

Neuroimaging Mechanisms and Neuromodulation Strategies for Neuropsychiatric Disorders

Neuropsychiatric disorders, encompassing conditions such as anxiety disorders, depression, sleep disorders, and Alzheimer's disease, significantly impair quality of life. This issue of the journal aims to investigate critical molecular targets within the neurotransmitter system, neuroplasticity, neurogenesis, neuroinflammation, and oxidative stress pathways, alongside the roles and mechanisms of compounds in modulating the neural molecular foundation and circuit regulation associated with these neuropsychiatric disorders. Employing advanced techniques, including magnetic resonance imaging (MRI), electroencephalography/magnetoencephalography (EEG/MEG), functional near-infrared spectroscopy... see more

Impact Factor: 5.3
Guest Editor(s): Dr. Liang Gong
Co-Guest Editor(s): Dr. Qing Ye,Dr. Hector W.H. Tsang,Dr. Bruijnzeel Adriaan W

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