Submission Tilte
Nano Formulations and Advanced Drug Delivery Approaches for Next-Generation Cancer Therapeutics.
Submission Abstract:
The field of oncology is undergoing a transformative shift with the integration of nanotechnology and advanced drug delivery systems aimed at enhancing the precision, efficacy, and safety of cancer therapeutics. Nano formulations—including liposomes, polymeric nanoparticles, dendrimers, micelles, and inorganic nanocarriers—offer unique physicochemical properties such as high surface area, tunable size, and controlled drug release, which allow for targeted delivery and improved bioavailability of chemotherapeutic agents. These systems are designed to overcome traditional challenges like poor solubility, multidrug resistance, and systemic toxicity.
Advanced delivery approaches, including stimuli-responsive systems (pH, temperature, enzymes), ligand-mediated targeting, and multifunctional nanoplatforms for theranostics, are enabling personalized and site-specific treatment strategies. Innovations like exosome-based delivery, hybrid nanoparticles, and CRISPR/Cas9-loaded nanocarriers represent the next frontier, offering potential for synergistic effects and gene-level interventions.
This concept for the proposed thematic issue highlights the latest progress in nano-based drug delivery systems for cancer therapy, examining their mechanisms, clinical advancements, and future potential in revolutionizing cancer treatment paradigms.