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Search Results: CDD
Current Drug Delivery
ISSN: 1567-2018 (Print)
eISSN: 1875-5704 (Online)
The journal aims to cover the latest outstanding developments in drug and vaccine delivery employing physical, physico-chemical and chemical methods. The drugs include a wide range of bioactive compounds from simple pharmaceuticals to peptides, proteins, nucleotides, nucleosides and sugars. The journal will also report progress in the fields of transport routes and mechanisms including efflux proteins and multi-drug resistance.
The journal is essential for all pharmaceutical scientists involved in drug design, development and delivery.
Special Issues With Active Call for Papers
Innovative Approaches in Drug Delivery Systems
The thematic issue “Innovative Approaches in Drug Delivery Systems” aims to cover current innovative applications in the field of drug delivery. This issue will focus on the latest developments in nanocarrier systems, tumor targeting, neurodegenerative diseases, inhalers, bioavailability, and topical applications. This issue will cover a wide range of topics, including the design and characterization of innovative nanocarrier systems, innovative pharmaceutical formulations for tumor targeting, innovative use of formulations for neurodegenerative diseases, future trends and... see more
Potential of Electrospinning for Current Drug Delivery
Electrospinning is a versatile polymer processing technology used for the fabrication of nanofibers. Nanofibers have been explored for drug delivery, tissue engineering, and biomedical applications. They have unique properties of high surface area, porosity, stability, and excellent morphology. The electrospinning technology has gained significant attention in recent years due to its ability to overcome the limitations of traditional drug delivery methods. The proposed thematic issue aims to explore the potential of electrospinning technology in revolutionizing... see more
Nanotechnology-Based Chemotherapy for the Treatment of Head and Neck Cancer
The escalating recurrence rates observed in head and neck cancer, particularly within the chemo-therapeutically treated cohort (50-60%), can be attributed to the non-selective nature of current anticancer drug delivery modalities. In this context, nanotechnology-based drug delivery systems emerge as a promising avenue for achieving precise localization of therapeutic agents to neoplastic sites via interaction with cell surface primer sites. The integration of nanotechnology in drug delivery holds potential for optimizing the pharmacokinetics, therapeutic efficacy, and... see more
Tumor-Targeted Drug Delivery Systems.
Tumor-targeted drug delivery systems present immense potential to revolutionize cancer treatment paradigms. This field, characterized by its intricate blend of material engineering, chemistry, biology, pharmacy, and pathology, constitutes a complex domain at the intersection of science and medicine. Thus, it is crucial to recognize the interdisciplinary structure of this field and promote communication among experts in various related fields from academia, clinics, and industry. The main goal of this section is to provide a comprehensive... see more
Innovative Nanomaterials for Enhanced Drug Delivery
The thematic issue "Innovative Nanomaterials for Enhanced Drug Delivery" aims to explore the forefront of nanotechnology applications in the field of drug delivery. This issue will highlight the latest advancements and breakthroughs in the design, synthesis, and implementation of nanomaterials that improve the efficacy, specificity, and safety of drug delivery systems. Nanomaterials have revolutionized the pharmaceutical landscape by enabling targeted delivery of therapeutics, reducing side effects, and enhancing the bioavailability of drugs. This issue will... see more
Extracellular Vesicles as Drug Delivery Systems.
Extracellular vesicles (EVs) are membranous vesicles released from almost all types of cells into extracellular space. EVs are categorized into different types including exosome (~30-150 nm), microvesicle or microparticle (~100-1,000 nm), apoptotic body (~1,000-5,000 nm), and others produced by different mechanisms. Since EVs bear the molecules (e.g., specific lipids, carbohydrates, proteins nucleic acids, etc.) derived from the cells and can be specifically recognized by adjacent or remote cells, EVs play an important role in cell-to-cell... see more
Pioneering Drug Delivery Strategies for Enhanced Cancer Immunotherapies
The landscape of cancer treatment has been fundamentally transformed by the advent of immunotherapy, a modality that harnesses the body's immune system to recognize and combat malignant cells. Despite its remarkable successes, the full potential of cancer immunotherapy is yet to be realized, largely due to limitations in targeted delivery, systemic toxicity, and tumor microenvironment-induced resistance. This special issue, "Pioneering Drug Delivery Strategies for Enhanced Cancer Immunotherapies," aims to showcase the latest advancements and innovative... see more
Electrospun Fibers as Drug Delivery Systems
In recent years, electrospun fibers have attracted considerable attention as potential platforms for drug delivery due to their distinctive properties and adaptability. These fibers feature a notable surface area-to-volume ratio and can be intentionally designed with high porosity, facilitating an increased capacity for drug loading and rendering them suitable for delivering both hydrophilic and hydrophobic drugs. The morphology of electrospun fibers can be customized to precisely control the release kinetics of drugs, with adjustments in... see more
Nanoemulsions in Cancer Therapy
Solid tumors are characterized by leaky vascular structure, defective angiogenesis, and high interstitial fluid load, providing opportunities for nanoparticles to preferentially exudate and be retained in tumors. This phenomenon is commonly referred to as the enhanced permeability and retention (EPR) effect, which is considered to be an important reason why nanoparticles can passively target tumors. Among the devised nanocarriers, nanoemulsions are currently being envisaged as an effective drug delivery approach for an array of chemotherapeutics because of their unique attributes... see more
Emerging Nanotherapeutics for Mitigation of Neurodegenerative Disorders
Conditions affecting the central nervous system (CNS) present a significant hurdle due to limited access to both treatments and diagnostic tools for the brain. The blood-brain barrier (BBB) acts as a barrier, restricting the passage of molecules from the bloodstream into the brain. The most formidable challenge facing scientists is comprehending and treating the mechanisms underlying neurodegenerative disorders, with a growing concern for neurodegenerative disorders, particularly in the cases of Parkinson’s, Alzheimer’s, ALS, and others.... see more
Recent Advances in Exosome-Based Drug Delivery for Cancer Therapy
Exosomes have garnered interest in the area of drug delivery. In the past ten years, there has been an exponential increase in the number of exosome-related studies in cancer. Preclinical studies demonstrate exosome-mediated delivery of chemotherapeutics, biologicals, and natural products that produce potent anticancer activity both, in vitro and in vivo. Exosome-based drug delivery systems present immense potential to revolutionize cancer treatment paradigms. The main goal of this section is to provide a comprehensive overview... see more
Advancements in Robotic and AI-Based Drug Discovery and Delivery for Neurological Disorders
Neurological disorders, including Alzheimer's disease, Parkinson's disease, epilepsy, and brain tumors, pose significant challenges in drug delivery due to the blood-brain barrier's intricate structure and the complexity of neuronal networks. Traditional drug delivery methods often fall short in reaching therapeutic concentrations within the central nervous system, limiting treatment efficacy and patient outcomes. This proposed special issue aims to address these challenges by showcasing the latest advancements in robotic and AI-based drug discovery and delivery systems... see more