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Current Drug Targets
ISSN: 1389-4501 (Print)
eISSN: 1873-5592 (Online)
Impact Factor :
3.0
Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.
As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.
Editor-in-Chief:
Center for Informational Biology
University of Electronic Science and Technology of China (UESTC)
China
Indexed in:
Jisc (Formerly: SHERPA/RoMEO), ScienceGate, Portico, Scopus, EMBiology, OpenAire, Index Medicus, MEDLINE/PubMed, Journal Citation Reports/Science Edition, Cambridge Scientific Abstracts (CSA)/ProQuest, Science Citation Index Expanded™ (SciSearch®), Essential Science Indicators, BIOSIS Previews, Biological Abstracts, Ulrich's Periodicals Directory, Suweco CZ, Scilit, QOAM, PubsHub, Norwegian Register, MediaFinder®-Standard Periodical Directory, JournalTOCs, J-Gate, Index Copernicus, Google Scholar, Genamics Journal Seek, ERA 2018, EMBASE, EBSCO, Dimensions, CNKI Scholar, Cabell's Directory/Journalytics, British Library... View all
Special Issues With Active Call for Papers
To Screen the Application of Small Molecule Targeted Drugs in the Field of Orthopedics by Artificial Intelligence
The integration of artificial intelligence (AI) into drug discovery and precision medicine has revolutionized therapeutic development, particularly in orthopedics, where small-molecule targeted drugs hold promise for treating bone-related disorders such as osteoporosis, osteoarthritis, and bone metastases. This thematic issue explores how AI-driven approaches, including machine learning, deep learning, and computational modeling, can accelerate the identification, optimization, and repurposing of small-molecule drugs for orthopedic applications. Topics of interest include AI-based drug screening, molecular docking simulations, predictive... see more
Progress in Drug Delivery, Therapeutic Strategies, and Nursing Practices: Enhancing Diagnostics and Clinical Outcomes in Complex Diseases
The recent advancements in drug delivery systems as well as therapeutics have significantly improved therapy effectiveness combined with better patient results specifically for difficult disease management. The modern pharmaceutical research field makes drug targeting its main priority because this approach strengthens therapeutic agents' precision while improving their effectiveness. Multiple delivery techniques such as ligand-based targeting and nanoparticle carriers with receptor-mediated approaches enable controlled delivery of drugs to specific target cells and tissues while minimizing general... see more
Emerging Drug Targets and Revolutionary Therapeutic Approaches for Effective Anti-Cancer Intervention
Recent advancements in cancer research have significantly advanced our understanding of the intricate molecular mechanisms driving cancer progression, leading to the identification of new drug targets and therapeutic strategies. The elucidation of complex signaling pathways and genetic aberrations associated with tumorigenesis has provided valuable insights into potential targets for intervention. Additionally, a paradigm shift towards revolutionary approaches such as targeted therapies, immune checkpoint inhibitors (e.g., PD-1-based immunotherapy), and adoptive cell therapies like CAR-T cell therapy... see more
New Drug Therapy for Eye Diseases
Eyesight is one of the most critical senses, accounting for over 80% of our perceptions. Our quality of life might be significantly affected by eye disease, including glaucoma, diabetic retinopathy, dry eye, etc. Although the development of microinvasive ocular surgery reduces surgical complications and improves overall outcomes, medication therapy is still an important strategy for many eye diseases, especially for the early stage of glaucoma, dry eye, and thyroid-associated ophthalmopathy. In recent decades, gene editing... see more
Therapeutic Chemical and RNA Design with Artificial Intelligence
Computer-Aided Drug Design (CADD) has emerged as a fundamental component of modern drug discovery. Molecular docking facilitates virtual screening on a large scale through structural simulations. However, traditional CADD approaches face significant limitations, as they can only screen known compounds from existing libraries. PubChem, as the most widely used chemical database, provides data on approximately 119 million compounds from 1,005 data sources (as of August 2024). Nevertheless, it is estimated that the pool of drug-like... see more
From Models to Molecules: Integrative Strategies in Herbal Product-based Drug Discovery
The toxic effects of synthetic drugs underscore the complex equilibrium between their therapeutic efficacy and the potential hazards they pose to biological systems. Natural products, with their diverse bioactive compounds and natural synergism, can help counteract synthetic drug toxicities by offering a complementary multi-targeted approach to mitigate organ damage and improve overall health. Natural products have long served as a cornerstone of drug discovery, offering unparalleled chemical diversity and bioactivity that continues to inspire modern... see more
Drug-Targeted Approach with Polymer Nanocomposites for Improved Therapeutics
Polymer nanocomposites have been recognized as an advanced and cutting-edge technique in drug targeting administration. These materials combine the unique features of nanoparticles with the adaptability of polymers to produce highly personalized drug administration devices. Integrating nanoparticles containing pharmaceuticals into a polymer matrix enables researchers to regulate the rates at which drugs are released, enhance the bioavailability of medicines, and selectively target particular cells or tissues. Consequently, this approach enhances the therapeutic effectiveness of pharmaceutical... see more