Submission Tilte
From Molecular Mechanisms to Therapeutic Frontiers: The Versatile Roles of Chaperones in Medicine
Submission Abstract:
Chaperones play critical roles in maintaining proteostasis by preventing protein misfolding and aggregation, which constitute central processes to the pathogenesis of numerous diseases such as neurodegeneration, cancer, and inflammatory disorders. This thematic issue will delve into the molecular mechanisms of chaperone function, their involvement in disease progression, and their potential as therapeutic targets. By combining cutting-edge research, including studies on chaperone modulation, molecular diagnostics, drug target validation and drug development, this issue aims to provide a platform for advancing our understanding of chaperones in molecular medicine. It will be a valuable resource for researchers and clinicians aiming to explore translational and clinical applications of chaperone biology.