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CNS & Neurological Disorders - Drug Targets

ISSN: 1871-5273 (Print)
eISSN: 1996-3181 (Online)

CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes. CNS & Neurological Disorders - Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of CNS & neurological drug targets. The journal also accepts for publication original research articles, letters, reviews and drug clinical trial studies. As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Special Issues With Active Call for Papers

Submission closes on: Jan 07, 2025
Heart and Brain Axis Targets in CNS Neurological Disorders

Recently there has been a surge of interest in delving deeper into the complex interplay between the heart and brain. This fascination stems from a growing recognition of the profound influence each organ holds over the other, particularly in the realm of central nervous system (CNS) neurological disorders. The purpose of this special issue is to meticulously explore and elucidate the identification and characterization of therapeutic targets that have the capacity to influence both cardiac... see more

Submission closes on: Jan 01, 2025
Lifestyle Interventions to Prevent and Treat Cognitive Impairment and Dementia

More than 55 million people live with dementia worldwide. By 2050, the population affected by dementia will exceed 139 million individuals. Mild cognitive impairment (MCI) is a pre-dementia stage, also known as prodromal dementia, affecting older adults. MCI emerges years before the manifestation of dementia but can be avoidable and reversible. Although individuals carrying the APOE E4 gene have a higher risk of Alzheimer’s Dementia, lifestyle is the major risk factor for the development of... see more

Submission closes on: Dec 08, 2024
Pathogenic Proteins in Neurodegenerative Diseases: From Mechanisms to Treatment Modalities

The primary objective of this thematic issue is to elucidate the molecular mechanisms by which pathogenic proteins contribute to neurodegenerative diseases and to highlight current and emerging therapeutic strategies aimed at mitigating their effects. By bringing together cutting-edge research and reviews, this issue aims to: 1.Enhance Understanding: Provide a comprehensive overview of the molecular pathways involved in the pathogenesis of neurodegenerative diseases. 2.Highlight Innovations: Showcase recent advancements in therapeutic interventions targeting pathogenic proteins. 3.Foster Collaboration:... see more

Submission closes on: Nov 13, 2024
Role of glial cells in autism spectrum disorder: Molecular mechanism and therapeutic approaches

Emerging evidence suggests that glial cells may play a pivotal role in neuroanatomical and behavioral changes found in autism spectrum disorder (ASD). Many individuals with ASD experience a neuro-immune system abnormalities throughout life, which implicates a potential role of microglia in the pathogenesis of ASD. Dysfunctional astrocytes and oligodendrocytes were shown to contribute to neurochemical imbalances and modifying axonal conduction in ASD. Altogether it is suggested that alterations in axons, myelin and exacerbated inflammation play... see more

Submission closes on: Jul 31, 2024
Novel Treatments in Subarachnoid Hemorrhage

The current landscape of therapeutic strategies for subarachnoid hemorrhage (SAH), a significant adverse neurological event commonly resulting from the rupture of intracranial aneurysms, is rapidly evolving. Through an in-depth exploration of the natural history of SAH, historical treatment approaches, and emerging management modalities, the present work aims to provide a broad overview of the shifting paradigms in SAH care. By synthesizing the historical management protocols with contemporary therapeutic advancements, patient-specific treatment plans can be individualized... see more