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Search Results: COC
Current Organic Chemistry
ISSN: 1385-2728 (Print)
eISSN: 1875-5348 (Online)
The frontier reviews provide the current state of knowledge in these fields and are written by selected experts who are internationally known for their outstanding research contributions. The journal also accepts high-quality research papers focusing on hot topics, highlights, and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.
Special Issues With Active Call for Papers
Porphyrazine, its Analogues and Their Metalcomplexes: Theoretical Consideration and Experimental Data
Porphyrazines are specific analogues of porphyrins – macrocyclic compounds with tetrapyrrole macrocycles, which are key components of a number of natural compounds, in particular chlorophyll and heme, playing a decisive role in the processes of reversible transfer of oxygen molecules in living organisms. They differ from porphyrins in that their meso-positions contain nitrogen atoms, not carbon atoms, as is the case in porphyrins. One of the most important representatives of porphyrazines is phthalocyanine, in which... see more
From Lab Bench to Algorithm: The Future of Organic Chemistry Powered by AI
Organic chemistry, with its intricate dance of molecules and reactions, is undergoing a transformation fuelled by the power of Artificial Intelligence (AI) and Machine Learning (ML). The integration of AI/ML with Organic Chemistry is revolutionizing the field by enhancing the efficiency and accuracy of chemical research and development. These technologies facilitate the prediction of molecular properties, reaction outcomes, and synthesis pathways, significantly accelerating drug discovery and material science advancements. AI/ML algorithms analyze vast datasets, identify... see more
Radical Nitrogen-Heterocyclic Carbene (NHC) Catalysis
Radical NHC catalysis as the new catalytic activation mode provides a powerful strategy for the construction of C-C/C-X bonds, which has attracted extensive attention from chemists around the world. Up to now, a great number of novel cross-coupling reactions for the generation of functional molecules have been developed via radical NHC catalytic process over the past years, and a series of valuable transformations have been reported accordingly. In which, the generation of persistent NHC-derived ketyl... see more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of those strategies on the development of the field of organic chemistry over the last 20 years is beyond description. More specifically, the functionalization of known... see more
Natural terpenes: The Chemistry and Biological Significance
Natural organic compounds such as alkaloid, flavonoid, terpene, protein, and saccharide have been widely applied in the fields of medicine, food supplements, agriculture, cosmetics and material sciences. Terpenes as an important natural products present intensively structural diversity and widely pharmacological properties. As an important origin of medicine, the chemistry and biological significance of natural terpenes have always been attractive to find out natural medicines or natural compound based medicines since ancient times. With the development... see more
N-Heterocyclics: Synthesis, Computational Studies, and Coordination Chemistry - A synthetic perspective
N-heterocycles, such as phenanthroline, quinoline, or their organometallic complexes, are widely used in a variety of fields, including chemistry, biochemistry, and coordination chemistry. They play a key role in many chemical and biological processes as biological ligands, medicinal agents, catalysts in organic synthesis, molecular probes and sensors, as well as fundamental structural units in metal-organic frameworks which have gained many industrial applications. N-heterocycles are also important synthetic intermediates in preparing a variety of biologically active... see more
Recent Advances in Catalytic Hydrogenations for Organic Syntheses
Catalytic hydrogenation is a typical reduction method in the fine chemical industry (e.g. pharmaceutical industry) for producing important and valuable organic chemicals. It can be realized both heterogeneous and homogeneous ways, but different selectivity (chemo-, regio- or stereoselectivity) problems can arise in case of more reducible functional groups. In addition, the reduction of compounds having catalyst poisoning character (typical substances containing nitrogen, phosphorus or sulphur) could be difficult, because the activity of the catalyst decreases... see more
Electrochemical C-X bond formation
Conventional methods for carrying out carbon–X bond formation are typically conducted at harsh reaction conditions, and rely on expensive catalysts as well as the use of stoichiometric, and perhaps toxic, oxidants. In this regard, electrochemical synthesis has recently been recognized as a sustainable and scalable strategy for the construction of challenging carbon–heteroatom bonds. Indeed, electrosynthesis has proven to be an environmentally benign, highly effective and versatile platform for achieving a wide range of nonclassical bond... see more
Synthesis of materials from natural or bioinspired substrates for multiplications
The aim of the topic is the synthesis of sustainable and versatile materials from naturally occurring or bio-inspired substrates. In today's day and age, the goal of the organic chemist is also to find new, environmentally sustainable, synthesis methodologies, which in turn can serve to obtain new systems that are as efficient and versatile as possible. The synthesis of eco-sustainable and biocompatible materials that are useful both in the field of catalysis, such as carbon... see more
Synthesis and Biological Evaluation of Nitrogen containing Heterocyclic Compounds
Heterocyclic compounds particularly Nitrogen containing compounds are important structural motifs in drug discovery and medicinal chemistry. Thus far a significant number of Nitrogen containing heterocyclic systems have been synthesized due to their wide range of synthetic utility. These heterocyclic compounds have a wide spectrum of biological activities such as anti-viral, anti- inflammatory, anti-fungal, anti-bacterial, anti-cancer, anti-malarial, anti-plasmodial, anti-tubercular, anti-hypertensive, anti-coagulant, diuretic, analgesic, anti-thrombic etc and also present in many natural products. Synthesis of such Nitrogen... see more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell surface recognition formulate the carbohydrate systems to be an exceedingly considerable scaffold for the development of new chemical entities of pharmacological importance. In addition to... see more
Unveiling New Pathways in the Progress of Heterocyclic Chemistry with Applications in Industry and Therapeutics.
This proposal introduces a special issue titled "Unveiling New Pathways in the Progress of Heterocyclic Chemistry with Applications in Industry and Therapeutics," aimed at fostering advancements in Heterocyclic Chemistry and its multifaceted applications. Heterocyclic compounds, pivotal in numerous industrial and therapeutic settings, represent a cornerstone of chemical and biomedical research. This special issue seeks to bridge the gap between innovative synthetic methodologies and their practical applications, catalyzing progress in pharmaceuticals, agrochemicals, materials science, and beyond.... see more
Organic Chemistry and Environmental Sustainability
The current scope of this Thematic Issue lies at the intersection of organic chemistry and environmental sustainability. It aims to spotlight innovative research that utilizes organic chemistry to address environmental challenges in the context of significant global changes, such as demographic shifts and the interconnectedness of food, energy, and water systems (National Intelligence Council, 2012). The issue focuses on the transformation of renewable raw materials into functional chemicals and fuels, a field that has seen... see more
Organic phytochemicals and analogues-Biosafety and healthcare applications
Increasing population and pollution become the biggest challenges for society. In contrast to traditional and conventional approaches, society has adopted synthetic medicinal practices as a major healthcare option which is rapid but also has serious side effects. Antibiotic resistance is one of the phenomena that came to light because of drug abuse. In contrast, traditional healthcare methods of different cultures belong to different countries including India (Ayurveda), China (traditional Chinese medicine), Korea (traditional Korean medicine),... see more