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Current Pharmaceutical Design

Journal Impact Factor: 3.2

Scopus Cite Score: 5.8

Indexed in: Scopus, SCI Expanded, MEDLINE/PubMed

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Aims and Scope:

Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Editor-in-Chief:

Alessandro Antonelli Department of Clinical and Experimental Medicine
University of Pisa
Pisa
Italy

ISSN: 1381-6128 (Print)

eISSN: 1873-4286 (Online)

Special Issues With Active Call for Papers

Submission closes on: Aug 05, 2027

Multi-Omics-Driven Drug Repurposing Across Disease Microenvironments: Decoding Molecular Heterogeneity for Precision Therapeutics

Disease microenvironments—including tumor niches, inflammatory lesions, fibrotic tissues, and metabolic compartments—exhibit profound molecular heterogeneity that fundamentally governs disease evolution, therapeutic resistance, and patient prognosis. Conventional one-size-fits-all therapeutic strategies often fail to account for this complexity, resulting in suboptimal clinical outcomes. Drug repurposing offers a compelling alternative by leveraging existing approved or investigational compounds for new indications, yet its success critically depends on a precise molecular understanding of the target microenvironment. This Special Issue aims to... see more

Impact Factor: 3.2
Guest Editor(s): Dr. Run Shi
Co-Guest Editor(s): Yongjie Wang,Jinjiang Chou

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Submission closes on: Apr 11, 2027

Sustainable Biopolymers in the Rational Design of Smart Drug Delivery Cargos

The integration of sustainable biopolymers into rational drug design has emerged as a transformative strategy in modern pharmaceutical development. Biodegradable and renewable polymers such as chitosan, alginate, cellulose derivatives, hyaluronic acid, gelatin, silk fibroin, and polylactide-based systems provide structurally versatile platforms for engineering advanced drug delivery cargos with precise control over drug loading, release kinetics, and targeting efficiency. This thematic issue aims to highlight recent mechanistic advances in the molecular design, physicochemical optimization, and functional... see more

Impact Factor: 3.2
Guest Editor(s): Dr. Abul Kalam Azad
Co-Guest Editor(s): Prof. Rizwan Khan,Dr. Mireia Mallandrich Mallandrich

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Submission closes on: Mar 21, 2027

Phenolic Nanocompounds in Inflammatory Disorders: Mechanisms, Therapeutic Potential, and Future Perspectives

Inflammation is a biological defence mechanism caused by several pro-inflammatory mediators that are produced by the immune system. Overproduction of these mediators produces chronic inflammation and may also be a reason for the various chronic disorders. For the inhibition of the inflammatory process, the available conventional treatment is costly and produces several side effects. Natural products are used extensively to overcome these types of problems. Phenolic compounds are very potent in inhibiting the inflammatory processes... see more

Impact Factor: 3.2
Guest Editor(s): Dr. Mohammad Kamal
Co-Guest Editor(s): Rupesh K. Gautam,Adel Abuzenadah

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Submission closes on: Feb 08, 2027

Pharmacological Study on the Prevention and Treatment of Cerebrovascular Diseases with Traditional Chinese Medicine

Cerebrovascular diseases (e.g., cerebral ischemia, hemorrhagic stroke, cerebral atherosclerosis) are leading causes of mortality and disability globally, posing heavy medical and social burdens. Traditional Chinese Medicine (TCM) has accumulated rich clinical experience in preventing and treating cerebrovascular diseases for thousands of years, with unique advantages in multi-component, multi-target, and holistic regulation. This thematic issue aims to highlight cutting-edge pharmacological research on TCM (including single herbs, active ingredients, and compound prescriptions) against cerebrovascular diseases. It will... see more

Impact Factor: 3.2
Guest Editor(s): Mr. Li Yu
Co-Guest Editor(s): Yue Hu,Cenglin Xu

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Submission closes on: Oct 23, 2026

Mapping Dynamic Sites and Designing Novel Therapeutics

The concept of allostery, where ligand binding at a site distinct from the active or orthosteric site modulates protein function, has emerged as a transformative paradigm in modern drug discovery. Unlike conventional orthosteric drugs that often face limitations in selectivity and off-target effects, allosteric modulators offer a promising alternative. Their inherent specificity, arising from the unique and less conserved nature of allosteric pockets, enables fine-tuned regulation of protein activity with minimal disruption to essential physiological... see more

Impact Factor: 3.2
Guest Editor(s): Dr. Mingkai Li
Co-Guest Editor(s): Lei Zhang,Prof. Lina Chen

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Submission closes on: Oct 16, 2026

The New Challenges of Precision Medicine for the Treatment of Thyroid Cancer

Thyroid cancer is a highly diffuse endocrine tumor whose incidence is worldwide rising. The most common histotype is the differentiated thyroid cancer (DTC), which includes the papillary thyroid cancer (PTC) and the follicular thyroid cancer (FTC). The prognosis for most of the DTC patients is favorable; however, tumors can dedifferentiate into more aggressive types not responding to conventional therapies. Therefore, for the most aggressive tumors, new therapies are needed, and the translational approach aids in... see more

Impact Factor: 3.2
Guest Editor(s): Dr. Giusy Elia
Co-Guest Editor(s): Silvia Martina Ferrari,Poupak Fallahi,Francesca Ragusa

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Submission closes on: Oct 08, 2026

Multidisciplinary Pharmaceutical Drug Design Strategies in the Progress of Drug Discovery

The process of developing a drug is time and money-consuming, but also fascinating. The development of numerous computational techniques, synthetic methodologies, formulation-based drug discovery, etc, has improved the drug discovery process. The process of developing new drugs is significantly hampered by drug-poor pharmacodynamics and pharmacokinetic problems. To address these challenges, several medicinal approaches/strategies from various fields are needed. In this view, the creation of effective drugs against the target site would require the incorporation of... see more

Impact Factor: 3.2
Guest Editor(s): Dr. Smriti Sharma
Co-Guest Editor(s): Dr. V. Murugesan

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Submission closes on: Oct 08, 2026

Rationale Approach for Nutraceutical Discovery, Development, and Delivery for Chronic Disease Management

The increasing burden of chronic diseases, such as cardiovascular disorders, diabetes, neurodegenerative diseases, inflammatory conditions, and cancer, has driven the demand for alternative and adjunctive therapeutic strategies. Nutraceuticals, derived from functional foods, dietary supplements, herbal extracts, and bioactive compounds, offer multi-targeted mechanisms, minimal side effects, and potential synergies with conventional pharmaceuticals. This thematic issue aims to explore innovative approaches in nutraceutical discovery, formulation strategies, application of nanotechnology, clinical validation, and ethical and regulatory aspects. Special... see more

Impact Factor: 3.2
Guest Editor(s): Dr. Manish Kumar Jeengar
Co-Guest Editor(s): Dr. Shafiul Haque,Prof. Dr. Kaladhar Kamalasanan,Dr. Jitendra Gour

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Submission closes on: Sep 05, 2026

Artificial Intelligence for Transformative Healthcare: From Prediction to Prevention

Machine learning and deep learning are transforming biomedical diagnosis by allowing for quicker and more accurate disease detection, ultimately enhancing patient care. Using advanced algorithms and extensive medical data, these approaches uncover patterns that may not be visible to humans, resulting in better detection of conditions such as cancer and heart disease. Deep learning in medical imaging has the potential to equal or surpass the skills of experienced clinicians, making the diagnosis of tumors, Alzheimer's,... see more

Impact Factor: 3.2
Guest Editor(s): Ajay Kumar

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