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Search Results: CPD
Current Pharmaceutical Design
ISSN: 1381-6128 (Print)
eISSN: 1873-4286 (Online)
Special Issues With Active Call for Papers
Food-derived bioactive peptides against chronic diseases
Chronic diseases, such as cardiovascular diseases and metabolic diseases, have become a great threat to the human health in recent decades due to the excessive food consumption and the prevalence of sedentary lifestyle. As a class of natural compounds, food-derived bioactive peptides have been demonstrated to possess great potential for the prevention and management of nutrition related chronic diseases. This special issue seeks to explore the latest research and developments in regard to the food-derived... see more
Diabetes mellitus: advances in diagnosis and treatment driving by precision medicine
Diabetes mellitus (DM) is a chronic degenerative metabolic disease with ever increasing prevalence worldwide which is now an epidemic disease affecting 500 million people worldwide. Insufficient insulin secretion from pancreatic β cells unable to maintain blood glucose homeostasis is the main feature of this disease. Multifactorial and complex nature of DM makes its diagnosis and treatment challenging. Genetic, epigenetic and environmental factors are the main risk factors that act independently as well as in interplay... see more
Blood-based biomarkers in large-scale screening for neurodegenerative diseases
Disease biomarkers are necessary tools that can be employ in several clinical context of use (COU), ranging from the (early) diagnosis, prognosis, prediction, to monitor of disease state and/or drug efficacy. Regarding neurodegenerative diseases, in particular Alzheimer’s disease (AD), a battery of well-validated biomarkers are available, such as cerebrospinal fluid Aβ42 and Tau, or specific neuropathological lesions detected by neuroimaging techniques. However, invasiveness and high cost limit the use of these biomarkers mostly in COUs... see more
The growing pandemic of Metabolic Dysfunction Associated Steatotic liver disease: diagnostic and treatment considerations
The scope of the present thematic issue will be to elaborate on the interconnection between metabolic dysfunction associated steatotic liver disease (MASLD) and other cardiometabolic co-morbidities and to discuss the impact of different therapeutic approaches on its progression and related complications, such as metabolic dysfunction–associated steatohepatitis (MASH), cirrhosis and hepatocellular carcinoma, recognizing the absolute need for tackling of this growing pandemic. see more
“Revolutionizing Cancer Treatment: Nano-Therapeutics Targeting Tumor Microenvironment”
This thematic issue explores the forefront of cancer treatment, centering on the groundbreaking potential of nano-therapeutics meticulously designed to target the tumor microenvironment. At its core, the issue aims to unravel the latest advancements in nanotechnology, showcasing innovative materials, formulations, and delivery systems that hold promise for redefining cancer therapeutics. The scientific community is invited to contribute research articles, reviews, and perspectives, shedding light on the intricate interplay between nano-therapeutics and the tumor microenvironment. A... see more
Emerging and re-emerging diseases
Faced with a possible endemic situation of COVID-19, the world has experienced two important phenomena, the emergence of new infectious diseases and/or the resurgence of previously eradicated infectious diseases. Furthermore, the geographic distribution of such diseases has also undergone changes. This context, in turn, may have a strong relationship with several factors, including climate change, evolution of microorganisms and decline in vaccination rates. As if that were not enough, the COVID-19 pandemic itself has also... see more
Sensitization of Tumors and Protection of Normal Tissues in Cancer Therapy by Natural and Synthesized Adjuvants
Cancer remains one of the most prevalent and devastating diseases worldwide. The development of effective therapeutic strategies to eradicate tumors while minimizing damage to normal tissues is a major focus of cancer research. In recent years, the field of cancer therapy has witnessed significant advancements in the use of adjuvants, both natural and synthesized, to sensitize tumors and protect normal tissues. Sensitization refers to the process of making cancer cells more susceptible to the action... see more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and pharmaceutical companies alike. By examining the latest advancements, emerging technologies, and unresolved issues, this issue seeks to foster a deeper understanding of the complexities involved... see more
Organic ligands coated metal oxide nanoparticles for biomedical Applications.
Organic Ligands coated metal oxide NPs: Two types of nanoparticles are focused that can be used for biomedical applications for instance, pure and organic ligands coated NPs. The pure NPs preferred for the external organs of the human or animal body. These particles are directly injected inside the tumor through injection. Moreover, the pure nanoparticles are used for the treatment of carcinoma and other biomedical applications. Here it is important to mention that coated nanoparticles... see more
"Tuberculosis Prevention, Diagnosis and Drug Discovery"
The Nobel Prize-winning discoveries of Mycobacterium tuberculosis and streptomycin have enabled an appropriate diagnosis and an effective treatment of tuberculosis (TB). Since then, many newer diagnosis methods and drugs have been saving millions of lives. Despite advances in the past, TB is still a leading cause of infectious disease mortality worldwide with more than 1 million deaths annually. It is also a major contributor to antimicrobial resistance. Thus, early diagnosis and treatment are the most... see more