The Open Bioinformatics Journal

Aims and Scope:
The Open Bioinformatics Journal is an Open Access journal, which publishes research articles, reviews/mini-reviews, letters, clinical trials and guest edited single topic issues in all areas of bioinformatics and computational biology. The coverage includes biomedicine, focusing on large data acquisition, analysis and curation, computational and statistical methods for the modeling and analysis of biological data, and descriptions of new algorithms and databases.

The Open Bioinformatics Journal, a peer reviewed journal, is an important and reliable source of current information on the developments in the field. Emphasis is placed on publishing quality papers rapidly, making them freely available to researchers worldwide.
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ISSN: 1875-0362

Special Issues With Active Call for Papers

Submission closes on: Jul 12, 2026
Machine Learning in Structural Bioinformatics: Predicting Protein Dynamics and Functional States

This thematic issue aims to explore the cutting-edge intersection of structural bioinformatics and machine learning, with a specific focus on predicting protein dynamics and alternative functional states. While tools like AlphaFold2 have made significant strides in static protein structure prediction, they still struggle to capture dynamic aspects like conformational transitions, intermediate states, and allosteric effects, which are vital for understanding protein function and druggability. The proposed issue will bring together state-of-the-art methodologies including stochastic MSA... see more

Guest Editor(s): Dr. Airy Sanjeev
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Submission closes on: Dec 31, 2025
Using immunogenomics and spatial proteomic mapping to detect cancer metastasis

The immune system uses adaptive immune response for protection against infections and tumor growth. Innate immune cells process invading pathogens and tumor cells. This leads of activation of T and B lymphocytes, which later develop into memory cells. Memory cells help to eliminate infected and tumor cells, but in rare occasions may cause significant damage to our own tissues, including autoimmunity. Autoimmunity refers to an aberration in the body's normal development that causes the immune... see more

Guest Editor(s): Dr. Daria Kessler
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