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Search Results: TOBIOIJ
The Open Bioinformatics Journal
ISSN: 1875-0362
The Open Bioinformatics Journal, a peer reviewed journal, is an important and reliable source of current information on the developments in the field. Emphasis is placed on publishing quality papers rapidly, making them freely available to researchers worldwide.
Special Issues With Active Call for Papers
Machine Learning in Structural Bioinformatics: Predicting Protein Dynamics and Functional States
This thematic issue aims to explore the cutting-edge intersection of structural bioinformatics and machine learning, with a specific focus on predicting protein dynamics and alternative functional states. While tools like AlphaFold2 have made significant strides in static protein structure prediction, they still struggle to capture dynamic aspects like conformational transitions, intermediate states, and allosteric effects, which are vital for understanding protein function and druggability. The proposed issue will bring together state-of-the-art methodologies including stochastic MSA... see more
Using immunogenomics and spatial proteomic mapping to detect cancer metastasis
The immune system uses adaptive immune response for protection against infections and tumor growth. Innate immune cells process invading pathogens and tumor cells. This leads of activation of T and B lymphocytes, which later develop into memory cells. Memory cells help to eliminate infected and tumor cells, but in rare occasions may cause significant damage to our own tissues, including autoimmunity. Autoimmunity refers to an aberration in the body's normal development that causes the immune... see more