Current Cancer Drug Targets

Journal Impact Factor: 3.5
Scopus Cite Score: 4.1

Indexed in: Scopus, SCI Expanded, MEDLINE/PubMed

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Aims and Scope:
Current Cancer Drug Targets aims to cover all the latest and outstanding developments in full spectrum of cancer drug discovery and development, including but not limited to cellular and molecular biology, genomics, proteomics, metabolomics, medicinal chemistry, pharmacology, toxicology, and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes and genes.
Current Cancer Drug Targets publishes original research articles, letters/commentary/perspectives, reviews / mini-reviews, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel drug targets for human anticancer drug discovery continues to grow, this journal has become essential reading for all biomedical and pharmaceutical scientists involved in drug discovery and development. Its scope covers publications related to prevention, diagnosis and treatment of all types of human cancers in various of basic and translational researches, including cancer etiology, signal transduction, biomarker, chemotherapy, hormone therapy, gene therapy, immunotherapy, radiotherapy, immunotherapy and combination therapy, stem cell, tumor environment, metabolism emphasizing on advanced mechanistic investigations.
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Editor-in-Chief:

  • Ruiwen Zhang Center for Drug Discovery
    University of Houston
    Houston, TX
    United States of America

ISSN: 1568-0096 (Print)

eISSN: 1873-5576 (Online)

Special Issues With Active Call for Papers

Submission closes on: Jan 04, 2027
Integration of Single-Cell Multi-Omics and AI: Decoding Immune Cell State Transitions for Precision Therapeutic Targeting

The dynamic plasticity of immune cells within the tumor microenvironment is a pivotal determinant of cancer progression and treatment response. While transformative, single-cell multi-omics technologies (encompassing transcriptomics, epigenomics, proteomics, and spatial profiling) generate datasets of immense complexity. The true power of this data is unlocked through its systematic integration with artificial intelligence (AI). This thematic issue will highlight pioneering research at this critical intersection. We seek contributions that employ integrative AI approaches—such as machine learning,... see more

Submission closes on: Aug 20, 2026
Emerging Targets and Therapeutic Strategies in Modern Cancer Drug Development

This thematic issue focuses on hot and emerging areas in cancer drug targets, aiming to compile 10-12 high-quality articles that explore cutting-edge research, including but not limited to the discovery of novel targets, development of targeted therapeutics, clinical translation of promising strategies, and addressing challenges like drug resistance. It seeks to integrate insights from diverse disciplines to advance the field of cancer drug targeting and enhance clinical outcomes. see more

Submission closes on: Aug 14, 2026
Tumor Metabolism and Immune Microenvironment

The tumor microenvironment is a complex ecosystem comprising tumor cells, immune cells, stromal cells, signaling molecules, and extracellular matrix components. Tumor metabolism and the immune microenvironment are two critical pillars of cancer biology that are deeply interconnected and play pivotal roles in cancer progression, treatment resistance, and immune surveillance. This thematic issue aims to explore the bidirectional interactions between tumor metabolism and the immune microenvironment, highlighting their synergistic effects on cancer development and therapeutic responses.... see more

Submission closes on: Jul 27, 2026
Molecular Targets and Emerging Therapies in Neuroblastoma

Neuroblastoma arises from the aberrant development of sympathetic neurons derived from the neural crest. Its pathogenesis remains unclear due to pronounced clinical, biological, and genetic heterogeneity. Despite advances in multimodal treatment, children with high-risk or advanced-stage neuroblastoma still face poor long-term survival. Moreover, intensive chemotherapy in early childhood often causes serious late effects, even in survivors. This Special Issue highlights recent progress in understanding the molecular and cellular basis of neuroblastoma, with a focus on... see more