Submission Tilte
Thematic Issue on Unleashing the Potential: Diverse Therapies and Innovative Drug Delivery Systems for Targeting Different Diseases
Submission Abstract:
Delivery systems for drugs have the potential to revolutionize the treatment of various diseases by enhancing drug efficacy, improving patient compliance, and reducing side effects. Review articles focusing on recent approaches and therapeutic applications of these systems can provide valuable insights to researchers and healthcare professionals. The aim of the present special issue is to contribute review articles by reporting the most recent approaches and their therapeutic applications using cutting-edge systems for drug delivery in various diseases. Moreover, articles on understanding how various disease states encourage research into developing therapeutic treatments that specifically target the disease are welcomed. Here's a brief overview of how improved delivery systems of drugs can be relevant to each of these conditions such as fungal nail infections can be challenging to treat due to the difficulty of penetrating the nail plate. Nanotechnology-based approaches like nail lacquers or hydrogels can be used to deliver antifungal agents to the site of infection, improving drug penetration and efficacy. Nanotechnology can aid in the delivery of therapeutic agents targeting the complications associated with sickle cell anemia. For instance, nanoparticle-based carriers can encapsulate drugs for reducing vaso-occlusive crises or promoting nitric oxide release to improve blood flow. For various chronic inflammatory conditions, nanoformulations can be employed to deliver anti-inflammatory drugs specifically to the affected joints. Nanocarriers can improve drug stability, prolong drug circulation time, and enhance drug accumulation within inflamed joints. This targeted drug delivery can help reduce systemic side effects and improve the therapeutic outcome. The development of target-specific medication delivery to the colon has been studied using a variety of techniques, including pH-dependent polymer, time-dependent, and bacteria-dependent drug delivery approaches. These techniques aim to enhance drug targeting to the colon, improve therapeutic efficacy, and minimize systemic side effects by reducing drug exposure in other parts of the gastrointestinal tract. They can be particularly beneficial for treating diseases such as IBD, where the colon is the primary site of inflammation, or for delivering drugs with potential side effects in the upper gastrointestinal tract. The special issue also recognizes the potential of phytosomes, a nanotechnology platform for phytochemical topical delivery, in the treatment of skin cancer. The applications of phytosomes in skin cancer treatment are an area of active research. Studies are being conducted to explore the effectiveness of phytosomal formulations in delivering anticancer phytochemicals to the skin, such as flavonoids, terpenoids, or polyphenols, for potential therapeutic benefits. These formulations can facilitate the skin's absorption of phytochemicals into the skin, increase their stability, and potentially improve their anticancer activity against skin cancer cells.
The special issue can shed light on their potential applications in different disease areas by highlighting the latest advancements in drug delivery systems. This may include topics such as targeted drug delivery, nanotechnology-based delivery systems, stimuli-responsive systems, personalized medicine approaches, and innovative delivery routes. Overall, the special issue has the potential to contribute to the advancement of therapeutic approaches and stimulate further research and development in the field of drug delivery systems, ultimately leading to improved treatments and outcomes for patients with different diseases.
