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Current Organic Chemistry
ISSN: 1385-2728 (Print)
eISSN: 1875-5348 (Online)
The frontier reviews provide the current state of knowledge in these fields and are written by selected experts who are internationally known for their outstanding research contributions. The journal also accepts high-quality research papers focusing on hot topics, highlights, and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.
Special Issues With Active Call for Papers
Radical Nitrogen-Heterocyclic Carbene (NHC) Catalysis
Radical NHC catalysis as the new catalytic activation mode provides a powerful strategy for the construction of C-C/C-X bonds, which has attracted extensive attention from chemists around the world. Up to now, a great number of novel cross-coupling reactions for the generation of functional molecules have been developed via radical NHC catalytic process over the past years, and a series of valuable transformations have been reported accordingly. In which, the generation of persistent NHC-derived ketyl... see more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of those strategies on the development of the field of organic chemistry over the last 20 years is beyond description. More specifically, the functionalization of known... see more
N-Heterocyclics: Synthesis, Computational Studies, and Coordination Chemistry - A synthetic perspective
N-heterocycles, such as phenanthroline, quinoline, or their organometallic complexes, are widely used in a variety of fields, including chemistry, biochemistry, and coordination chemistry. They play a key role in many chemical and biological processes as biological ligands, medicinal agents, catalysts in organic synthesis, molecular probes and sensors, as well as fundamental structural units in metal-organic frameworks which have gained many industrial applications. N-heterocycles are also important synthetic intermediates in preparing a variety of biologically active... see more
Recent Advances in Catalytic Hydrogenations for Organic Syntheses
Catalytic hydrogenation is a typical reduction method in the fine chemical industry (e.g. pharmaceutical industry) for producing important and valuable organic chemicals. It can be realized both heterogeneous and homogeneous ways, but different selectivity (chemo-, regio- or stereoselectivity) problems can arise in case of more reducible functional groups. In addition, the reduction of compounds having catalyst poisoning character (typical substances containing nitrogen, phosphorus or sulphur) could be difficult, because the activity of the catalyst decreases... see more
Electrochemical C-X bond formation
Conventional methods for carrying out carbon–X bond formation are typically conducted at harsh reaction conditions, and rely on expensive catalysts as well as the use of stoichiometric, and perhaps toxic, oxidants. In this regard, electrochemical synthesis has recently been recognized as a sustainable and scalable strategy for the construction of challenging carbon–heteroatom bonds. Indeed, electrosynthesis has proven to be an environmentally benign, highly effective and versatile platform for achieving a wide range of nonclassical bond... see more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell surface recognition formulate the carbohydrate systems to be an exceedingly considerable scaffold for the development of new chemical entities of pharmacological importance. In addition to... see more
Synthesis of materials from natural or bioinspired substrates for multiplications
The aim of the topic is the synthesis of sustainable and versatile materials from naturally occurring or bio-inspired substrates. In today's day and age, the goal of the organic chemist is also to find new, environmentally sustainable, synthesis methodologies, which in turn can serve to obtain new systems that are as efficient and versatile as possible. The synthesis of eco-sustainable and biocompatible materials that are useful both in the field of catalysis, such as carbon... see more
Unveiling New Pathways in the Progress of Heterocyclic Chemistry with Applications in Industry and Therapeutics.
This proposal introduces a special issue titled "Unveiling New Pathways in the Progress of Heterocyclic Chemistry with Applications in Industry and Therapeutics," aimed at fostering advancements in Heterocyclic Chemistry and its multifaceted applications. Heterocyclic compounds, pivotal in numerous industrial and therapeutic settings, represent a cornerstone of chemical and biomedical research. This special issue seeks to bridge the gap between innovative synthetic methodologies and their practical applications, catalyzing progress in pharmaceuticals, agrochemicals, materials science, and beyond.... see more
Organic Chemistry and Environmental Sustainability
The current scope of this Thematic Issue lies at the intersection of organic chemistry and environmental sustainability. It aims to spotlight innovative research that utilizes organic chemistry to address environmental challenges in the context of significant global changes, such as demographic shifts and the interconnectedness of food, energy, and water systems (National Intelligence Council, 2012). The issue focuses on the transformation of renewable raw materials into functional chemicals and fuels, a field that has seen... see more
Organic phytochemicals and analogues-Biosafety and healthcare applications
Increasing population and pollution become the biggest challenges for society. In contrast to traditional and conventional approaches, society has adopted synthetic medicinal practices as a major healthcare option which is rapid but also has serious side effects. Antibiotic resistance is one of the phenomena that came to light because of drug abuse. In contrast, traditional healthcare methods of different cultures belong to different countries including India (Ayurveda), China (traditional Chinese medicine), Korea (traditional Korean medicine),... see more
Cutting-edge technology for the development of electrochemical sensors
Electrochemistry based point of care diagnostics is a powerful tool which can revolutionize the current concept of personalize health care industry. There have been several efforts to amalgamate cutting edge technologies (nanotechnology, surface technology, anti-biofouling strategies) while developing assays. The success of each electrochemical sensor is very dependable upon how we build the chemistry. Here we focus onto discussing chemistries which eventually shows hope to overcome the sufferings and major challenges the electrochemical sensing devices... see more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are also included in the scope of the thematic issue. see more
Functional Chitosan: Recent Gamma Radiation Chemistry of Organic Derivatives.
This Special Issue will cover the recent radiation chemistry of chitosan (CS) and the attempts that researchers have made to prepare a plethora of derivatives for diverse synthetic applications. The cutting-edge science carried out by experts regarding the gamma-radiation-induced synthesis methods, types of monomers used for grafting the CS, and enhanced properties of the new organic compounds are provided here. see more
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for plant protection, their frequent application has led to issues such as resistance in plant disease, environmental contamination, and risks to human health. Therefore, it may... see more
Ionic Liquids in the Catalysis Process
This special issue delves into the multifaceted applications of ionic liquids, emphasizing their pivotal role in catalysis, immobilization techniques, and green chemistry initiatives. We invite contributions that unravel the catalytic mechanisms of ionic liquids, showcase innovative immobilization strategies, and highlight their sustainable applications. From biomass conversion to eco-friendly processes, this collection aims to provide a comprehensive understanding of how ionic liquids contribute to advancing green and sustainable practices across various domains. see more
Recent Advances in Asymmetric Aminocatalysis
Aminocatalysis has indeed emerged as a significant cornerstone of asymmetric catalysis. In the forthcoming thematic issue, we will delve into how novel activation modes successfully address intricate stereoselective transformations. Aminocatalytic strategies catalyze a revolution in various chemistry domains, including natural product synthesis, drug discovery, and fine chemicals production. Notably, enantioselective aminocatalysis has been recognized as one of the ten emerging technologies in Chemistry, with the potential to contribute to a more sustainable planet, as acknowledged... see more
Green tools to produce biomaterials from agroindustrial wastes
Green tools to produce biomaterials from agroindustrial wastes represent a promising and sustainable approach to address both environmental and resource challenges. These innovative techniques leverage agroindustrial byproducts, such as crop residues and food processing waste, to produce valuable biomaterials, including bioplastics, biofuels, and biochemicals. By utilizing eco-friendly and renewable resources, these processes not only reduce the environmental footprint of waste disposal but also contribute to a circular economy. Green tools often involve biotechnological methods, such... see more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods and machine learning to gain deeper insights into organic catalysts behavior and reaction mechanisms, using these tools to predict electronic structures and reaction pathways more... see more