Endocrine, Metabolic & Immune Disorders - Drug Targets

Journal Impact Factor: 2.0
Scopus Cite Score: 4.4
Aims and Scope:
This journal is devoted to full-length/ mini-reviews and original articles based on experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbiome composition are welcome. The journal’s scope also covers neuroendocrinology, reproductive endocrinology, hormone secretion, and their effects on different organs.
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Editor-in-Chief:

  • Emilio Jirillo Department of Basic Medical Sciences Neuroscience and Sensory Organs
    University of Bari “Aldo Moro”
    Bari
    Italy

ISSN: 2212-3873

Special Issues With Active Call for Papers

Submission closes on: Aug 21, 2026
Advances in Targeting the Gut–Microbiota–Immune Axis in Metabolic Disorders

This special issue aims to explore the rapidly evolving field of the gut–microbiota–immune axis and its critical role in the development, progression, and treatment of metabolic disorders. By highlighting current research and innovative therapeutic strategies, the issue seeks to advance our understanding of how modulating gut microbiota and immune interactions can offer new avenues for managing metabolic disorders. see more

Impact Factor: 2.0
Guest Editor(s): Dr. Manish Gautam
Co-Guest Editor(s): Phool Chandra,Sandip Mondal
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Submission closes on: Feb 22, 2026
Advances in Therapeutic Strategies: Bridging Endocrine, Metabolic, Cancer and Immune Disorders for Precision Medicine.

The intricate interplay between endocrine, metabolic, and immunological disorders, addressing the challenges posed by their overlapping pathophysiology. With a focus on diseases such as diabetes, obesity, autoimmune thyroid conditions, and systemic inflammatory disorders, it highlights the transformative potential of precision medicine. Advances in genomics, transcriptomics, proteomics, and metabolomics are uncovering novel biomarkers and therapeutic targets, enabling personalized treatment strategies tailored to individual molecular profiles. The issue showcases cutting-edge research and translational initiatives, emphasizing innovative therapies... see more

Impact Factor: 2.0
Guest Editor(s): Dr. H. K. Verma
Co-Guest Editor(s): Dr. Manish Verma,Dr. Areena Siddiqui
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Submission closes on: Jan 03, 2026
Advancing Therapies for Bone and Joint Diseases: Insights from Natural Products and Herbal Medicines

The aging global population is experiencing an increased risk of bone and joint health issues, notably osteoporosis and osteoarthritis, affecting over half of individuals over 60. Plant-based natural products and herbal medicines are gaining recognition as alternative therapies for these conditions, with secondary metabolites, including flavonoids, coumarins, and others, playing a pivotal role in their pharmacological activity. For example, salicylic acid, a COX-2 inhibitor, was the first natural substance employed as a therapeutic intervention for... see more

Impact Factor: 2.0
Guest Editor(s): Dr. Lingfeng Zeng
Co-Guest Editor(s): Prof. Claudio Lucchiari,Prof. Wen-Hua Ling,Prof. Jian-Ping Liu
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Submission closes on: Dec 31, 2025
Immune defense of the blood-tissue barriers which are related to drugs, metabolic and hormones

We have already known that testis is an immune privilege area for the maintenance of spermatogenesis against to any pathogen from the interstitial area. With the BTB integrity there is a qualified selection for the mature sperm until the lumen migration which is sperm release progress. Spermiogenesis help for the sperm morphology to get its expected pattern for the fertilization with its packaged DNA and its cytoplasmic proteins and miRNAs. In summary, in IVF clinics,... see more

Impact Factor: 2.0
Guest Editor(s): Dr. Nazlı Ece Ordueri
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Submission closes on: Dec 31, 2025
Association between Diabetes Mellitus and natural product complementary applications: State of the arts

Diabetes Mellitus (DM) represents a significant global health challenge, characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The increasing prevalence of DM, alongside its associated complications, has prompted researchers and healthcare professionals to explore a variety of management strategies beyond conventional pharmacotherapy. Among these strategies, the use of natural products as complementary applications has garnered considerable interest. Natural products, derived from plants, herbs (as called phytochemicals) and from other... see more

Impact Factor: 2.0
Guest Editor(s): Dr. Mostafa Gouda
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Submission closes on: Dec 31, 2025
Chronic inflammation and Disorders/Cancers

Chronic inflammation is fundamental cause of variety of disorders. Many lifestyle-related diseases including metabolic syndrome, obesity, impairment of immune responses, sepsis, mental illness, and other disorders are caused by chronic inflammation. Prevention of chronic inflammation is related to antiaging effects of our body. Proinflammatory cytokines such as TNF-α is associated with chronic inflammation. Cancer is one of the ultimate forms of chronic inflammation and its related progression may also depend on a latent chronic inflammatory... see more

Impact Factor: 2.0
Guest Editor(s): Dr. Kazuki Santa
Co-Guest Editor(s): Dr. Elsa Vitale
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